Course M1474

M1474 Microscopy Without the Microscope:
New Ways to Guide Clinical Decision Making


Tuesday, September 9, 2014
4:00-5:00 PM

1.0 CME Credit

Learn about new optical methods that have been developed that may upend conventional ways of examining tissues. These approaches can generate cellular images, even from inside the patient, and may supplement or replace conventional microscopy techniques. Some, like optical coherence tomography and confocal endomicroscopy, are in clinical practice. Others, such as multiphoton microscopy, are emerging but promising, and may achieve clinical traction. The cost and complexity of technologies vary, but there will be major impacts on clinical workflow and biopsy numbers: imaging can improve biopsy yield while decreasing biopsy numbers. Immediate therapy with the elimination of biopsies may be an eventual outcome. Related developments in imaging specimens immediately after resection may replace standard frozen section, and possibly routine histology. Improved surgical guidance and accelerated patient care would be among the benefits.

You will learn to:

  • Develop a basic understanding of optical imaging
  • Identify in vivo microscopy methods currently in clinical use
  • Recognize emerging technologies that impact diagnostic pathology


Richard M. Levenson, MD, FCAP